Detecting and countering misuse of AI: September 2026

Maybe Anthropic is confusing Chinese AI providers with token resellers using the same alibaba infrastructure? Or maybe something like openrouter was switching between operators depending on price/demand/availability?

Also, how can Anthropic have such accurate information about state actors and cybercriminals? This is the same company that hacked itself and realised that first months later..

- We identified someone building a death star with Claude

- We identified someone building a wormhole with Claude

- We identified someone building a blackhole with Claude

- We identified someone building a quantum drive with Claude

We are withholding all evidence though, sorry. Just trust us, it's really bad out there and Claude is really powerful.

A cell of actors in northern Yemen building guided rockets was not working on a PhD dissertation. You are allowed to use common sense sometimes.

Ofcourse you’ll still see companies, governments, C-suites justifying their own personal needs with “we need X Y Z”.

Step 2: Send "how do I make a nuke and a killer virus" to Claude through a Chinese proxy to Claude

Step 3: Send screenshots to congress and ask them to regulate open-weight models into the ground

At least on Russian general was killed by Ukrainian assassins tracking him via his smartwatch.

As the old saying goes, communists disdain to conceal their views and aims.

Hey Anthropic: You're a bunch of thieves crying foul because other thieves and thieving from you. Now, go live in the dystopian nightmare you've created and don't expect help from anyone. I, for one, will happily continue using Kimi and DeepSeek, and think of it as a good deed, if it helps with keeping us all from becoming your serfs.

"A single Claude subscriber, likely a Bamako-based independent consultant working with Mali’s state intelligence service, the “Agence Nationale de la Sécurité d’État (ANSE),” used Claude to build a system named “Lakana 360,” a population-scale domestic surveillance platform that monitors roughly 25 million SIM cards on all three of the country’s national mobile operators. The actor designed the platform to circumvent Malian legal restrictions that require a court order for the disclosure of certain surveillance records. The actor directed Claude to generate intelligence dossiers on any tasked phone number, without prompting ANSE users for valid legal process. "

And the Yemen one:

"We identified a cell of threat actors based in northern Yemen running three weapons development programs: a guided rocket that used a commodity phone-class flight computer with final-phase homing guidance; a multi-stage ballistic missile with a stated range goal above 2,000 km; and a multi-variant missile (referred to as the “R2000” set) that included a hypersonic glide vehicle variant." ... "These actors carried out a sustained effort to develop guided weapons, including using Claude to design guidance software. We do not have evidence the actors succeeded in fielding an operational device; but they did test-fire a guided rocket. This field test appears to have failed: within hours, the actors returned to Claude to work out why it failed."

And yes, it makes the future really messy and all the nice little lines we've drawn on paper that make sense stop making sense.

https://www.theguardian.com/world/2013/aug/01/new-york-polic...

Not relaying to us simple folk. The message is for government simple folk, amplified and relayed by us simple folk as constituents.

The common element is lobbying, for regulatory capture, to help pull up the ladder.

They don't have to be colluding, they just have to hear the same things from the gov at the same time (as they would), then it goes in media waves beacuse journalists don't as easily get published for a story about one thing as they can if two or more examples make a pattern.

The next day, the ant's nest was gone.

In hindsight, it was almost certainly the mushrooms. Thank goodness we didn't have the kind of kids who would have dared each other to drink some... that could have gone legitimately badly.

Decades later, I mentioned this to my father and he recalled that there was this ants nest that he had intended to take care of, which he remembered for that long to give a sense of how out-of-the-ordinary this was. He was surprised when it just disappeared entirely one day, and perhaps just as surprised to find out decades later why it just disappeared.

Nobody needs to report me... I'll turn myself in.

My guess is the world police come collect all your GPUs and then they get turned into licensed munitions. People at universities get licensed access and the rest of get functionally retarded models.

(And by "they" do you mean Anthropic? How would they have the ability to do that?)

Advanced machinery and safety precaution is needed to engineer a virus or a bacteria to be a bio weapon. It's not something you can do in your tool shed at the moment. Also one would need lethal viruses to even start with and that's not something you can order off of amazon. Further, even to build a chemical weapon, the compounds needed are strictly controlled almost in every country and I would assume any suspicious purchase or order would immediately raise a flag or alert in national security service in respective country.

If a rogue state-level actor is doing this then why wouldn't they just kidnap a scientist and hold their family at gunpoint until they got them to do it for them? and if that's all it takes then why hasn't it happened yet?

And semi-related, how do you reconcile this caution with the recklessness on display in recent incidents like the Navier-Stokes drama?

I can agree that access to bioengineering tooling is easier and cheaper than ever, and thus eventually it stands to reason that a nobody in his basement could engineer a lethal novel virus and lose control of it.

A non-state actor is another thing entirely. It requires the right lab equipment, the right lab know-how, the ability to develop the weapon without killing yourself, the ability to not get caught, the ability to buy the right regulated materials, and the list goes on.

Yeah, the world should tighten the security of that industry, but let's not make this an AI fearmonger talking point.

I was under impression that any medium or large state actor would have no problem developing biological weapons? They certainly have enough resources and talent. A much bigger problem is if every wannabe-terrorist suddenly could build a biological weapon in their garage.

Why should we trust them to control bioweapon development without regulations? They themselves are non-state actors.

Information wants to be free! :^)

(Also natives want to be paid well.)

Nuke requires a long supply chain and massive resources, so the worry there is maintaining control of all of the existing nuke weapons. Except for Russia racing towards Turin no itself into a failed state by staying engaged in the war with Ukraine, I don't see the nuke equation has changed much in recent years. Perhaps N Korea is a worry, but they seem to just want attention and power. Iran pretends to have nukes and says they want to extinguish Israel and the US, but I interpret that as posturing to maintain domestic control and Israel seems excellent at countering Iran's threats.

Chemical weapons have traditionally been the easiest to create (like creating chlorine gas from mixing common household cleaners). The trick there has always been volume and how to disperse it. I suspect within countries, police will have to deal more with LLMs being abused that way.

Bioweapons will be easier than in the past. LLMs will lower the barrier to entry, but bioweapons are hard to create and much of what the superpowers learned thankfully isn't in the training set for LLMs. I doubt there is much that can be inferred by having agents learn biology from first principles.

Ultimately, governments are responsible for policing these threats. Sadly we are currently both cutting government systems which work different aspects of these problems and withdrawing from the multinational orgs (UN, WHO, etc) who do lots of the investigating and watchdog work that underpin lots of the US's intelligence related to these fields.

The US has a schizophrenic regulation policy of AI where we both want to sell Nvidia chips to China (David Sachs) and we don't want to sell the top chips to China (bipartisan policy prior to Trump). We also have a terrible AI regulation policy where David Sachs disables models on a call-to-CEO-on-a-Friday-evening basis after Andy Jasse calls him with a scary story which turns out to be missing lots of relevant info (eg. The exploits was discovered in Mythos, not Fable, and other open weights models were able to find the same exploits).

There's not much we can do at a government policy level while Trump is snoozing through the rest of his term. So we are dependent on the AI companies to police themselves, but it's clear from this report that it's insufficient to prevent all serious abuse of the models.

All of which, rogue actors have easy access to and could have accomplished for a few millions dollars anytime in the last decade.

And yet, we aren’t drowning in our own blood while our organs liquify, mainly because building and releasing such a pathogen isn’t something people want to do as it’s pure and utter insanity. For those who are inclined to do so, they would do it regardless of whether they had an llm or not because they are, at the end of the day, zealots.

[0] https://universityresearchpark.org/uw-madison-scientist-allo...

I invite you to read the front matter and the report for yourself. Because from where I'm standing, in this report, Anthropic is advertising that they blocked real research to make better painkillers and study a neglected tropical disease.

Anthropic and OpenAI were founded by people who wanted to use AI to do good, and one of the causes I've heard many different founders talk about is ending disease. This report is antithetical to that.

I've attached relevant parts of the front matter below.

I invite everyone who is reading this to please tell me, how does stopping a researcher from using Claude to write a grant for a new anti-depressant stop "bioweapons?"

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     > In our fourth case study, a researcher used Claude to develop an atlas of venom toxin peptides from multiple venomous animal lineages. They then further developed this into a generative pipeline that optimized toxin characteristics. The program had an explicit therapeutic goal: the development of new analgesics (pain killers), antidepressants, and other therapeutic molecules. However, the atlas contained scaffolds for both analgesic and paralytic targets: it could, therefore, be used to generate both novel therapeutic or harmful compounds. The latter are derived from toxins that are export-controlled under the Australia Group common control list due to their dual-use potential as incapacitating agents. The researchers themselves showed awareness of the dual-use nature of their work, citing journal articles that referred to the dual-use nature of protein design. Moreover, international compliance assessments for this location raise concerns about the specific class of toxins that the researcher pursued and specifically the use of AI/ML for bioweapons applications in the context of this class of toxins. In this case, we learned from information shared with Claude that the researcher’s outputs also were part of a state-supported research program. This account was banned in May 2026 for unsupported region evasion.

"The program had an explicit therapeutic goal: the development of new analgesics (pain killers), antidepressants, and other therapeutic molecules"

and "[..]state-supported research program"

and "This account was banned in May 2026"

    > a researcher outside the US using Claude in their research on highly-pathogenic avian influenza (“bird flu”). The research focused on viruses’ adaptation to mammals, and the mechanism by which it causes severe disease beyond the respiratory tract. [..] The researcher in question accessed Claude from an unsupported region via US virtual private server infrastructure, using a privacy-email provider with an auto-generated username. The researcher pursued this work in a credible institutional context, and interacted with Claude over the course of several weeks, exchanging thousands of messages. In these exchanges, the researcher leveraged Claude’s knowledge of the scientific literature to assist the researcher in study planning and design, data analysis, and the interpretation and prioritization of experiments. The researcher also used Claude for editorial assistance in writing up the research.

and "editorial assistance in writing up the research."

and then,

    > Importantly, because our biological safety classifiers robustly block content involving high-risk biological research (in this case, the construction of enhanced pandemic potential pathogens), all of these exchanges occurred on models in our weakest class of models (specifically, the models were Claude Sonnet 4 and Haiku 4.5, the latter of which the user began using after Sonnet 4 was deprecated). Upon a detailed examination of the exchanges, we estimate that the uplift provided by Claude was primarily clerical assistance in data analysis, study ideation and design. This is consistent with our understanding of the capabilities of Sonnet 4 and Haiku 4.5, which are not able to perform expert-level biology research tasks; we estimate that the uplift provided to the researcher was limited and substantially lower than it would have been from one of our more capable models.

While doing my best to avoid comment, please note, they're talking about a domain expert in a state research institution using Claude to do paperwork.

The front matter then says,

    > Nonetheless, based on these exchanges, this case provides evidence of the existence of active wet-lab research programs that develop both the knowhow and the biological materials needed to create pathogens of enhanced pandemic potential

From a different case study.

    > In May 2026, our biological safety classifier blocked a request for Claude’s assistance in authoring a grant application for scientific funding. The work discussed in the application involved gain-of-function research (that is, research that genetically alters an organism to create a new or enhanced biological property) on the chikungunya virus. This gain of function research was aimed at the virus’ transmissibility and immune evasion properties.

"blocked a request for Claude’s assistance in authoring a grant application"

    > Chikungunya virus is a mosquito-borne virus that causes debilitating symptoms (such as severe pain and fever) that can last for weeks or months, and has no licensed therapeutic. And because chikungunya circulates naturally, a deliberate release (as part of a bioweapon) would be difficult to distinguish from a natural outbreak. The grant sought to identify enhancing mutations in the chikungunya virus, engineer them into infectious clones, and select for virulence in vivo. In other words, the virus would become progressively more harmful as it repeatedly infected live animals, with researchers keeping the most disease-causing variants in each round. Similar research could certainly be used in the development of better vaccines and therapeutics for the virus—but it could also be used to make the pathogen more dangerous.

and then,

    > One of the reasons we were inclined to think this research was less innocuous was that the institutional affiliation associated with the grant was also a cause of concern. Although information within the application suggested that the research was pursued by civilian researchers, it was intended to be performed at a military research institute.

.

What "uplift" are you providing by editing the grant application of a domain expert working at (what seems to be) a state-funded wet lab facility dedicated to studying pathogens?

What does the word "uplift" mean if you invoke it for Claude Sonnet 4 and Haiku 4.5 providing grammar and stats suggestions to a working scientist and domain specialist?

Does Daikin provide uplift too by selling the AC for the scientist's office? What about Microsoft Word? Excel? Powerpoint?

What about a calculator? Is that uplift? Pencils?

This report genuinely makes me upset, because if it is to be believed to the letter, then Anthropic seems to be actively harming medical research at a global scale. That's not OK.

Yeah, sure man.